1.comfortable adj 安逸的，舒服自在的

反义词 ：uncomfortable

comfortably adv。

2. 搭配：

be comfortable doing sth

be comfortable about 对……感到轻松或无忧虑

They didn’t feel comfortable about her travelling alone.

他们对她独自旅游感到担忧。

Lots of people don't feel comfortable about public speaking.

许多人对当众讲话感到不自在。

be comfortable with sb 和某人相处感觉自在

I don’t feel comfortable with him. 和他相处我感到不自在。

She’s never felt very comfortable with them.

她和他们在一起从来都觉得不自在。

be comfortable with sth 对某事轻松接受

Is everyone comfortable with the arrangement?

这样的安排大家都满意吗？

另外，comfortable的反义词uncomfortable也有类似用法。如：

He felt uncomfortable about accepting the gift.

他对收下礼物感到不安。

He was uncomfortable about telling such a blatant lie.

他对说了那样无耻的谎言而感到不安。