区别就是两者意思都是可以表示在我家，具体的不同如下！

in my home中文意思是在我家里

I pour myself some cereal and gulp it down in my home office while waiting for the computer to boot up.

in my family中文意思是在我家庭里I was the first in my family to go to college.

In my home 是在我家里的意思，而In my family则是在我家庭里的意思。区别可以从以下例子看出：

There are many furniture in my home, these are all precious treasures in my family, belong to my wife, and our children. 我家有很多家具，这些都是我家庭的宝贵财富，属于我的妻子和我们的孩子。