They abandoned themselves to drinking. 他们沉湎于饮酒。

Rescuers had abandoned all hope of finding any more survivors. 救助人员放弃了继续寻找生还者的希望。

abandon a friend in trouble 抛弃处于危难中的朋友

give up: I can’t answer that puzzle; I give. 我猜不出这个谜语，我认输了。

desert: Never desert a friend in need. 绝不要抛弃需要帮助的朋友。

quit: I want to quit smoking. 我想戒烟。

forsake: She persuaded her husband to forsake his drinking habit. 她说服丈夫改掉嗜酒的习惯。

leave: He is scheduled to leave for London next Monday. 他预定于下周一动身去伦敦。